Severe breast pain and tenderness. Some women have a higher risk of developing painful breast conditions than others. Breast pain can also be associated with starting to take or changing contraception that contains hormones. If your GP thinks you may have non-cyclical breast pain or chest wall pain, they may ask you to lean forward during the examination. Cyclic pain varies with hormonal fluctuations. In some cases, a biopsy of the area is also needed. Tell us where we can send you your copy. However, a systematic review concluded that vitamins make no difference. Engorgement occurs when your breasts become overfull.